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Reducing Adverse Cardiovascular and Renal Outcomes in Type 2 Diabetes Population


This may appear to be intuitive to every health care provider but it is in fact an elusive goal not necessarily discussed or much less emphasized on day-to-day management of diabetes at the primary care sites.
Cardiologists, vascular surgeons, neurologists and nephrologists are usually engaged at a later stage when organ damage has already occurred and may be permanent. Endocrinologists and diabetologists are in short supply and tend to be referred the hard to control patients in need of better blood sugar control and frequently type 1 diabetics or type 2 patients of longer vintage. This leaves a vast population of individuals who carry a clear and powerful risk for the development of vascular disease with manifestations such as stroke, heart attack, loss of limb kidney failure and premature death. We are now in a new era with pharmacotherapy available and validated in randomized studies as being capable of altering the trajectory of these very poor outcomes including agents that stimulate the action of upper intestine peptides called incretins, agents that impede the reabsorption of glucose in the renal tubule and a specific blocker of the mineralocorticoid receptor. In my view the digital medical record should serve as an instrument to make use of these agents' part and parcel of the discussion around sugar control and a mandatory reminder of missed opportunities regarding interventions solely aiming at improved outcomes sometimes dissociated from blood sugar control. Primary care providers are inundated with too much data as they are the repository of information coming from all sources in formats that are not at all conducive to finding the main message. The end result is to concentrate on what is palpable and address the more immediate needs of the patients.Type 2 diabetes as well as chronic kidney disease are multipliers of cardiovascular risk of greater magnitude than lipids